Ibuprofen lysinate is a nonsteroidal anti-inflammatory agent with potent analgesic and anti-inflammatory effect, due to its inhibition of the synthesis and/or release of prostaglandins.
In patients with primary dysmenorrhoea ibuprofen decreases the elevated prostaglandin levels in the menstrual fluid, decreases the intrauterine pressure and the frequency of uterine contractions.
The advantage of ibuprofen lysinate over ibuprofen alone is the shorter period of absorption by the gastrointestinal tract, owing to the higher solubility level of lysinate. This enables a faster action onset, already within 15-20 minutes.
The benefits of ibuprofen are its lowest incidence of adverse effects – comparable to placebo, as well as the most favourable benefit-risk ratio.
The recommended daily dose is 200-400 mg every 4-6 hours.
The maximum daily dose is 1.2 g, which is by 6 times higher than the amount 1 Caffetin Menstrual tablet contains.
One Caffetin Menstrual tablet contains 200 mg ibuprofen, which is equivalent to 342 mg ibuprofen lysinate.